Endocrine Abstracts

According to the American Diabetes Association (ADA), achieving specific treatment goals in type 2 diabetes can substantially reduce microvascular complications, including retinopathy, nephropathy and neuropathy. Intensive management has also been shown to have a beneficial effect on cardiovascular disease. The objective of the study is to evaluate the degree of achievement of appropriate target levels for A1C, as an index of chronic glycaemia, LDL-c and blood pressure, in a l...

Pituitary dysfunction is a common, treatable consequence of traumatic brain injury (TBI), and is associated with poorer outcomes. Identifying prognostic factors that allow targeted endocrine testing will ensure that patients at higher risk of pituitary dysfunction are identified and screened.Analysis of 176 adults at least 6 weeks after TBI attending the multidisciplinary Imperial TBI clinic found an overall prevalence of pituitary dysfunction of 13.7% (...

Background: Cushing’s syndrome (CS) is considered to be more frequent among patients with metabolic syndrome. Previous studies have suggested to perform a routine screening for CS in obese patients; however, more recent reports only recommend a case-finding approach in patients with uncontrolled diabetes and hypertension, despite appropriate treatment.Objective: The aim of this study was to evaluate the prevalence of unsuspected CS in morbidly obese...

Background: Previous studies have suggested that serum thyroglobulin (Tg) levels at the time of 131I remnant ablation just after thyroidectomy, could be a prognostic tumor marker in differentiated thyroid cancer (DTC).Objective: The aim of this study was to evaluate if serum preablation Tg in the earliest postoperative period could be useful for predicting persistence or recurrence of disease.Methods: This study was a retrospective...

In our country, as in others, there is a lack of data on the success rate of transsphenoidal surgery for producing pituitary adenomas. We evaluated the results reported in TESSPAIN, a retrospective multicenter nationwide project that includes all the TSS performed in the participating centers in the period between 2018 and 2022, both included. Surgical treatment success is defined according to the published criteria for each disease: normal IGF-1 and GH after 75 g of oral gluc...

Transsphenoidal surgery (TSS) of the hypothalamic-pituitary region is the approach of choice because of its lower morbidity compared to the transcranial approach. However, its results are highly variable and depend on many factors related to the tumor itself, to the medical team, and to technical issues. We review the situation of this procedure in a nationwide retrospective multicenter evaluation. Data were collected from centers participating in the TESSPAIN (TranssphEnoidal...